CirclesDiamondBlueThiner
TitleBlues

MutaBind2 evaluates the effects of mutations on protein-protein interactions for soluble complexes. It calculates changes in binding affinity upon single or multiple mutations and provides a structural model of mutated complex. The structure of a protein-protein complex is required for this method. MutaBind2 is the second version of MutaBind method. The method can be used for SARS-CoV-2 modeling.

Complex4


Step 1 - Select Protein Complex


Example: 1CSE
Bioassembly
Asymmetric Unit


Reference

Zhang N, Chen Y, Lu H, Zhao F, Alvarez RV, Goncearenco A, Panchenko AR, Li M. MutaBind2: Predicting the Impacts of Single and Multiple Mutations on Protein-Protein Interactions. iScience. PMID: 32169820


School of Biology & Basic Medical Sciences, Soochow University
199 Ren-Ai Road, Suzhou, Jiangsu, 215123 P.R. China
Contact Us