MutaBind2 evaluates the effects of mutations on protein-protein interactions for soluble complexes. It calculates changes in binding affinity upon single or multiple mutations and provides a structural model of mutated complex. The structure of a protein-protein complex is required for this method. MutaBind2 is the second version of MutaBind method.
Zhang N, Chen Y, Lu H, Zhao F, Alvarez RV, Goncearenco A, Panchenko AR, Li M. MutaBind2: Predicting the Impacts of Single and Multiple Mutations on Protein-Protein Interactions. iScience. PMID: 32169820