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MutaBind2 evaluates the effects of mutations on protein-protein interactions for soluble complexes. It calculates changes in binding affinity upon single or multiple mutations and provides a structural model of mutated complex. The structure of a protein-protein complex is required for this method. MutaBind2 is the second version of MutaBind method.

Complex4


Step 1 - Select Protein Complex


Example: 1CSE
Bioassembly
Asymmetric Unit


Reference

Zhang N, Chen Y, Lu H, Zhao F, Alvarez RV, Goncearenco A, Panchenko AR, Li M. MutaBind2: Predicting the Impacts of Single and Multiple Mutations on Protein-Protein Interactions. iScience. PMID: 32169820


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